الخميس , نوفمبر 23 2017
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معجون أسنان عسل مانوكا _ MANUKA HONEY TOOTHPASTE

معجون أسنان عسل مانوكا _ MANUKA HONEY TOOTHPASTE

قسم الأبحاث والتطوير

د/ سامح ربيع احمد

معجون أسنان عسل مانوكا

الخصائص:

يعتبر معجون أسنان عسل المانوكا مفهوما جديدا لمعاجين الاسنان لما يحتوي عسل المانوكا على خصائص طبية مهمة جدا لا توجد في غيره من أنواع العسل، حيث أثبتت بعض الدراسات

(1) ان عسل مانوكا له القدرة على محاربة الرقائق الحيوية الملتصقة والتي تمثل العامل الأساسي لتسوس الأسنان كما أثبتت الدراسات (2) (3) (4) أيضا احتواء عسل المانوكا على عدد من المضادات الحيوية المضادة لانواع من البكتريا مثل ستربتوكوكاي وغيرها من البكتريا التي تستوطن الفم وتسبب تسوس الأسنان.

كما أن الخاصية المضادة للالتصاق الحيوي(1) (2) تساعد أيضا على منع تكون طبقة الجير الصفراء على الأسنان وتزيلها. إن إضافة زيت القرنفل بالنسبة الملائمة لمعجون أسنان مانوكا يعطيه خاصية شد اللثة والتغلب على الكثير من مشاكلها.

 

Kilty et al., (2011): Methylglyoxal: (active agent of manuka honey) in vitro activity against bacterial biofilms. International Forum of Allergy & Rhino logy. 1(5): 348-350.

(2) Badet, C., and Quero, F., (2011): The in vitro effect of manuka honeys on growth and adherence of oral bacteria. Anaerobes. 17: 19-22.

(3) Packer et al., (2012): Specific non-peroxide antibacterial effect of manuka honey on the Staphylococcus aureus proteome. International Journal of Antimicrobial Agents. 40:43– 50.

(4) Abdelmalek et al., (2012): Antibacterial activity of honey alone and in combination with Nigella sativa seeds against Pseudomonas aeruginosa infection. Asian Pacific Journal of Tropical Disease . S428-S430

 

معجون مانوكا

What is Manuka honey?

Manuka honey:

is a natural monofloral – extracted from one plant species and has distinctive flavor- honey that obtained from nectar of manuka tree which grows in New Zeland and Australia. It has antimicrobial [1,2] and anti biofilm[3,4,5] activities.

Biofilms and dental plaques:

Dental plaque is the diverse microbial community found on the tooth surface embedded in a matrix of polymers of bacterial and salivary origin [6]

Effects of Manuka Honey:

Exploring existing research databases revealed Manuka honey biological properties –in vitro and in vivo- ranging from anti-oxidant, anti-inflammatory, anti-bacterial, anti-viral, anti-biotic and wound healing, anti biofilm,[3,4,5] anti-tumor to immune- simulator properties. Methylglyoxal is the unique compound in the honey responsible for some of its potent anti-microbial properties.[1]

(1)

(1)

(2)

(2)

(3)

(3)

Badet C and Quero F.The in vitro effect of manuka honeys on growth and adherence of oral bacteria. Anaerobe(2011) 17:19-22*

(4)

(4)

(5)

(5)

(6)

(6)

The Effects of Manuka Honey on Plaque and Gingivitis:

Results of some studies suggest that there may be a potential therapeutic role for manuka honey in the treatment of gingivitis and periodontal disease.[3,7]

One study investigated whether or not manuka honey with an antibacterial activity rated UMF 15 could be used to reduce dental plaque and clinical levels of gingivitis.[7]

Amazing Results:

A chewable “honey leather” was produced for this trial. Thirty volunteers were randomly allocated to chew or suck either the manuka honey product, or sugarless chewing gum, for 10 minutes, three times a day, after each meal. Plaque and gingival bleeding scores were recorded before and after the 21-day trial period. Analysis of the results indicated that there were statistically highly significant reductions in the mean plaque scores (0.99 reduced to 0.65; p=0.001), and the percentage of bleeding sites (48% reduced to 17%; p=0.001), in the manuka honey group, with no significant changes in the control group.[7]

Manuka Tree Flower

Manuka Tree Flower

 

 

[1] PATEL S and CICHELLO S. Manuka honey: an emerging natural food with medicinal use. Nat. Prod. Bioprospect. (2013) 3:121–128.

[2] Mandal MD. Mandal S. Honey: its medicinal property and antibacterial activity. Asian Pacific Journal of Tropical Biomedicine (2011)154-160.

[3] Badet C and Quero F.The in vitro effect of manuka honeys on growth and adherence of oral bacteria. Anaerobe(2011) 17:19-22

[4] Alandejani T et al. Effectiveness of honey on Staphylococcus aureus and Pseudomonas aeruginosa biofilms. Otolaryngology–Head and Neck Surgery (2009) 141: 114-118.

[5] Cooper R et al. Inhibition of biofilms through the use of manuka honey. Wounds uk, (2011) 7(1): 24-32.

[6] Marsh PD and Bradshaw DJ. Dental plaque as a biofilm. J Ind Microbiol. (1995) 15(3):169-75.

[7] English HK. The effects of manuka honey on plaque and gingivitis: a pilot study. J Int Acad Periodontol. (2004) 6(2):63-7.

 

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